General Articles
11:15 a.m. 1.Sep.99.PDT
The trouble started early this morning when scientists announced that they had created a strain of smart mice by inserting a gene into the rodents' brains, proving it possible to improve the intelligence of mammals, including humans. The strain of genetically modified mice, named Doogie, were given extra copies of a gene called NR2B which helped them to learn faster and to improve their memory.
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"They're learning things much better and remembering longer. They're smarter," said Joe Tsien, a neurobiologist at Princeton University.
The NR2B gene could also be a potential drug target to eventually treat learning disorders and diseases involving the decline or loss of memory, such as Alzheimer's, researchers said.
Tsien said the study showed that genetic improvement of learning and memory in mammals was feasible. He likened the enhanced learning in the mice to increasing the speed of a top-performance car.
But a sports car is dangerous when it goes out of control and these mice were no different. While attempting to draw some fluid from a third generation test mouse, the mouse suddenly stirred, biting one of the researchers. He was quickly rushed out of the facility for medical attention. Unfortunately the mice broke free in the confusion and ran rampant through the facility causing extensive damage to the elevators that resulted in the staff being trapped in the facility.
As they struggled desperately to get out of the research facility the mice began stalking the staff and attacking at inopportune moments. Several researchers were savagely nibbled before anything could be done. Things brightened a bit when the cook trapped one of the mice in the cafeteria oven and cooked it. Later one of the scientists electrocuted another mouse. Dr. McAnister was plugging a lamp back in and discovered that one of the mice had been chewing on the cord.
Order was eventually restored. The staff managed to get out of the facility but discovered that the last mouse had as well. Luckily for everyone it was promptly run over in the parking lot before it could get away. If the mouse had reached safety and bred with normal mice, there is no telling what might have happened.
A visibly shaken McAnister admitted later that they had made a mistake by tampering with nature in this way.
Inspired by this news story.
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